How do you get Burkholderia pseudomallei?
The disease is most common in people that have exposure to contaminated water or soil in areas of the world where the disease is common.
- Melioidosis (Burkholderia pseudomallei)
- Reporting Melioidosis.
What is Burkholderia pseudomallei infection?
Melioidosis, also called Whitmore’s disease, is an infectious disease that can infect humans or animals. The disease is caused by the bacterium Burkholderia pseudomallei. It is predominately a disease of tropical climates, especially in Southeast Asia and northern Australia where it is widespread.
Which disease is caused by P pseudomallei organism?
melioidosis. melioidosis, a bacterial infection in humans and animals caused by Pseudomonas pseudomallei. Transmission to humans occurs through contact of a skin abrasion with contaminated water or soil rather than through direct contact with a contaminated animal.
Is Burkholderia pseudomallei motile?
Burkholderia pseudomallei, a facultatively intracellular pathogen, is a flagellated and motile gram-negative bacterium and is the causative agent of melioidosis in humans.
What kills Burkholderia pseudomallei?
pseudomallei is susceptible to many antimicrobial agents, and the U.S. Centers for Disease Control and Prevention (CDC) recommends meropenem or ceftazidime as IV therapies and TMP-SMX or doxycycline as oral therapy. Other choices include aminoglycosides, tetracycline, chloramphenicol, and amoxicillin-clavulanate.
Where is Burkholderia pseudomallei found in the body?
Melioidosis can be diagnosed by isolation and identification of Burkholderia pseudomallei. Bacteria may be found in blood, sputum, tissues and wound exudates.
Is Burkholderia pseudomallei contagious?
Burkholderia pseudomallei, the bacteria that causes Melioidosis (or Whitmore’s disease), was first discovered in 1911 by pathologist Alfred Whitmore and his assistant. What is Melioidosis? Melioidosis is a highly contagious disease primarily infecting people in areas with agriculture and farming.
What does Burkholderia pseudomallei look like?
Burkholderia pseudomallei (also known as Pseudomonas pseudomallei) is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. It is a soil-dwelling bacterium endemic in tropical and subtropical regions worldwide, particularly in Thailand and northern Australia.
Is Burkholderia pseudomallei a lactose fermenter?
Burkholderia pseudomallei as we know is a non-fermentor of lactose. However, it appears as pink-colored colonies in MacConkey agar media following 48hours of incubation.
Is there a cure for Burkholderia pseudomallei?
Depending on the clinical manifestations of the disease, treatment for B. pseudomallei is usually biphasic, starting with 10–14 days of intravenous therapy, followed by weeks to months of oral eradication therapy.
How long does Burkholderia pseudomallei live on surfaces?
Surfaces: B. pseudomallei does not require an animal reservoir. It can persist in a dry environment and remain infectious and culturable for hours to days. In addition, it can remain infectious, viable and non-culturable for up to 1 year.
What is the most likely route of natural infection with Burkholderia pseudomallei?
There have only been a few documented cases of person-to-person transmission; percutaneous inoculation is probably the most frequent route for natural infection. In contrast to other healthcare personnel, laboratory personnel are at risk because some procedures may aerosolize particles and release B.