What is Piptaz used for?

Piperacillin and tazobactam injection is used to treat pneumonia and skin, gynecological, and abdominal (stomach area) infections caused by bacteria.

What type of drug is Piptaz?

Piperacillin and tazobactam combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors. It works by killing the bacteria and preventing their growth.

How do you administer Piptaz?

Piperacillin/Tazobactam 2 g / 0.25 g is administered by intravenous infusion (over 30 minutes). Piperacillin/Tazobactam 4 g / 0.5 g is administered by intravenous infusion (over 30 minutes).

What is the action of inj Piptaz?

Piptaz 4.5gm Injection is a combination of two medicines. It is used to treat bacterial infections like tonsillitis, sinusitis, otitis media, respiratory tract infections, urinary tract infections, boils, abscesses, cellulitis, wound infection, bone infection and oral cavity infections.

When do you give Piptaz?

The dosage of PIPTAZ is generally 4.5g every eight hours. The dose may vary between 2.25g and 4.5 g and may also be given every six hours. For children aged 2 to 12 years, weighing up to 40 kg, and with normal kidney function, the recommended dosage is 112.5 mg/kg (100 mg piperacillin/12.5 mg tazobactam) every 8 hours.

How do you dilute Piptaz?

Reconstitute the pharmacy bulk vial with exactly 152 mL of a compatible reconstitution diluent, listed below, to a concentration of 200 mg/mL of piperacillin and 25 mg/mL of tazobactam. Shake well until dissolved.

What are the side effects of piperacillin tazobactam?

SIDE EFFECTS: Swelling, redness, pain, and soreness at the injection site may occur. Dizziness, trouble sleeping, nausea, vomiting, diarrhea, and headache may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What is the side effect of injection Piptaz?

Nausea, constipation, diarrhea, headache, or trouble sleeping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Is Piptaz hepatotoxic?

Hepatotoxicity. Patients on intravenous piperacillin may have transient and mild-to-moderate serum aminotransferase elevations in up to 12% of patients, but these are of little clinical significance and not more common than with comparative parenteral antibiotics.

Can Piptaz cause hypernatremia?

A secondary effect of piperacillin/ tazobactam therapy is hypernatremia as was noted in this patient. To conclude, hypokalemia is a known but uncommon adverse effect of piperacillin/tazobactam therapy.

Does Piptaz cause hypokalemia?

Hypokalemia is a serious adverse effect of piperacillin-tazobactam and should be suspected while treating patients with this drug. Early recognition and prompt withdrawal of the drug will result in lesser morbidity.

How can I protect my liver while on antibiotics?

However, if overused, they can cause long-term changes to healthy gut bacteria and contribute to liver damage.

1. Take Probiotics During and After Treatment.
2. Eat Fermented Foods.
3. Eat Prebiotic Foods.
4. Avoid Certain Foods That Reduce Antibiotic Effectiveness.

What antibiotics can cause liver damage?

Liver injury caused by drugs such as azithromycin (known as Z-Pak) and amoxicillin/clavulanate (Augmentin) can occur within one to three weeks. Patients with drug-induced liver injury may experience nausea, itchy or yellowing skin, and abdominal pain and have dark urine.

Is Piptaz compatible with potassium?

No interactions were found between piperacillin / tazobactam and Potassium Chloride in Sodium Chloride.

Does piperacillin tazobactam cause hypernatremia?

Is Piptaz compatible with dextrose?

Piperacillin sodium 40 mg/mL plus tazobactam in 5% dextrose injection was visually compatible with the majority of the drugs tested for up to four hours at 22 degrees C but incompatible with 24 drugs.

What is the name of the drug Piptaz?

The name of your medicine is PIPTAZ. It contains the active ingredients piperacillin and tazobactam. They belong to a group of antibiotics called penicillins that work by killing bacteria. Piperacillin is an antibiotic that kills many types of bacteria.

What are the side effects of Piptaz?

Prescribing Piptaz in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of development of drug-resistant bacteria. The most common adverse reactions are diarrhea, constipation, nausea, headache and insomnia. (6.1)

Is Piptaz a beta lactamase inhibitor?

The presence of tazobactam in the Piptaz formulation enhances and extends the antibiotic spectrum of piperacillin to include many β-lactamase producing bacteria normally resistant to it. Thus, Piptaz combines the properties of a broad spectrum antibiotic and a β-lactamase inhibitor.

What are the different types of infections can be treated with Piptaz?

PIPTAZ is active against bacteria which cause serious infections such as: – 1 Chest infections 2 Urine infections 3 Stomach infections 4 Skin infections 5 Gynaecological infections 6 Septicaemia (blood poisoning).