What is infiltrative myocardial disease?
Infiltrative cardiomyopathy (ICM) refers to a heterogeneous group of myocardial disorders mainly cardiac amyloidosis, sarcoidosis, and hemochromatosis with characteristic deposition of abnormal substances within cellular and intercellular spaces, which leads to the development of ventricular diastolic dysfunction.
What is infiltrative process?
Infiltration is the diffusion or accumulation (in a tissue or cells) of foreign substances in amounts excess of the normal. The material collected in those tissues or cells is called infiltrate.
What is happening during the myocardial disease process?
Myocardial ischemia occurs when blood flow to the heart muscle (myocardium) is obstructed by a partial or complete blockage of a coronary artery by a buildup of plaques (atherosclerosis). If the plaques rupture, you can have a heart attack (myocardial infarction).
Is infiltrative cardiomyopathy hereditary?
Infiltrative cardiomyopathies result from progressive buildup of abnormal substances in the heart. Several infiltrative cardiomyopathies are inherited and have known genetic mechanisms.
How long can you live with peripartum cardiomyopathy?
The estimated mortality rate associated with peripartum cardiomyopathy in the United States is 6% to 10%. Death usually occurs within 30 days but has occurred later as well.
What does infiltration mean medically?
Infiltration is the accidental leakage of non-vesicant solutions out of the vein into the surrounding tissue. This can occur with many antibiotics, dextrose solutions, or even normal saline.
Does infiltrating mean invasive?
Cancer that has spread beyond the layer of tissue in which it developed and is growing into surrounding, healthy tissues. Also called invasive cancer.
What is the life expectancy of restrictive cardiomyopathy?
Outlook (Prognosis) People with restrictive cardiomyopathy may be heart transplant candidates. The outlook depends on the cause of the condition, but it is usually poor. Survival after diagnosis may exceed 10 years.