Is Sprycel better than Gleevec?

NEW YORK (Reuters) – Bristol-Myers Squibb’s cancer drug Sprycel was superior to the highly effective Gleevec in treating newly diagnosed patients with chronic myeloid leukemia, researchers reported on Saturday.

Is dasatinib a chemo drug?

Generic Name: Dasatinib SPRYCEL is the trade name for the generic chemotherapy drug Dasatinib. In some cases, health care professionals may use the trade name SPRYCEL when referring to the generic drug name Dasatinib. Drug Type: SPRYCEL is a targeted therapy.

What is dasatinib used for?

Dasatinib is used to treat Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in adults and children. It is also used to treat Ph+ CML and Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) in adults after other medicines (eg, imatinib) or treatments did not work well.

What is the brand name for dasatinib?

SPRYCEL® (dasatinib) is a prescription medicine used to treat: Adults with newly diagnosed Philadelphia chromosome–positive (Ph+) chronic myeloid leukemia (CML) in chronic phase (CP) Adults with Ph+ CML who no longer benefit from, or did not tolerate, other treatment, including imatinib.

How long does it take for Sprycel to work?

Sprycel begins working shortly after you start taking it. Your body may begin to respond to the drug within 1 to 2 months. Some people who took Sprycel had a complete response (no sign of cancer cells in two bone marrow tests). This result was seen after about 3 months of treatment, in studies.

How long can you take dasatinib?

Sprycel is used as a long term treatment and in clinical trials has been taken for 5 years. You usually keep on taking it as long as: your tests show it is working well. your condition has not worsened.

What is dasatinib made of?

SPRYCEL tablets are white to off-white, biconvex, film-coated tablets containing dasatinib, with the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, hydroxypropyl cellulose, and magnesium stearate.

What is the target of dasatinib?

Dasatinib is a multi-target kinase inhibitor, whose targets include BCR-ABL, SRC family kinases, and various cancer kinases. The elevated SRC activity in gastric cancer (GC) has prompted the need for the therapeutic application of dasatinib in GC.

Can dasatinib cure CML?

The standard treatment for chronic phase CML is a tyrosine kinase inhibitor (TKI) like imatinib (Gleevec), nilotinib (Tasigna), dasatinib (Sprycel), or bosutinib (Bosulif).

What is the newest drug for CML?

Scemblix is the first FDA-approved CML treatment that works by binding to the ABL myristoyl pocket, and represents an important development for patients who experience resistance and/or intolerance to currently available TKI therapies1-3.