Is Myozyme still available?

Is Myozyme still available?

Last updated on Aug 6, 2020. The Myozyme brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.

What is Myozyme used for?

What is Myozyme used for? Myozyme is used to treat patients who have Pompe disease, a rare inherited disorder. Patients with Pompe disease do not have enough of an enzyme called alpha-glucosidase. This enzyme normally breaks down sugar stored as glycogen into glucose that can be used for energy by the body’s cells.

What is the difference between Myozyme and Lumizyme?

Myozyme is indicated for infantile-onset Pompe disease; Lumizyme is indicated for patients aged ≥8 years. Although both drugs have been shown to improve patient survival rates, they both also have a boxed warning, because of the possibility of life-threatening allergic reactions.

How is Myozyme administered?

The recommended dosage of Myozyme is 20 mg per kg of body weight. It will be given to you once every 2 weeks. The recommended dosage of Myozyme in children and adolescents is the same as in adults. Myozyme is given through a drip into a vein (by intravenous infusion).

How much does Myozyme cost?

Myozyme, which inspired the Harrison Ford movie Extraordinary Measures, costs up to $100,000 for a child. But according to Genzyme, the average cost of adult treatment is $300,000 per year.

How is enzyme replacement therapy done?

Enzyme Replacement Therapy: The Basics The most common method of ERT is through IV infusions, in which the replacement enzyme is administered directly into the bloodstream through a controlled drip of fluids.

How do I infuse Myozyme?

Infusions should be administered incrementally. MYOZYME should be administered at an initial infusion rate of no more than 1 mg/kg/hr. The infusion rate may be increased by 2 mg/kg/hr every 30 minutes, after patient tolerance to the infusion rate is established, until a maximum rate of 7 mg/kg/hr is reached.

Why are prescription drugs so much cheaper in Canada?

Prescription drugs are cheaper in Canada because of federal and provincial government policies that essentially act as price controls. The U.S. generally does not control and negotiate down prescription drug prices, with the exception of the Department of Veterans Affairs and the Medicaid program.

Which is highest price medicine?

1. Zolgensma (API Onasemnogene abeparvovec-xioi) In May 2019, FDA approved new gene therapy for SMA, and with the price tag of $2,125,000, it’s the most expensive drug the world has ever seen.

What are the disadvantages of enzyme replacement therapy?

However, there are certain disadvantages: Not all patients are suited for this treatment. Some organs and tissues are treated more readily than others and there are problems with gauging efficacy. They are expensive, thereby limiting access to patients.

What are the side effects of enzyme replacement therapy?

As with any medication, enzyme replacement therapy may have side effects. These include irritation at the site where the IV is inserted, electrolyte imbalance, fever, or an allergic reaction. Additional symptoms may include headaches, tremors, chest tightness, nausea, and/or vomiting.