What are the benefits of therapeutic drug monitoring?
What is the Importance of Therapeutic Drug Monitoring? Therapeutic drug monitoring helps in designing patient-specific dosage regimen; it aids in enhancing the efficacy of drugs, to reduce the toxicity of drugs and for diagnostic purposes, by individualizing drug therapy.
What is the single most important factor in therapeutic drug monitoring?
Accurate timing of sample collection is often an important factor in TDM, especially when timed samples such as peak or pre-dose (trough) samples are the primary means of monitoring.
What is the goal of therapeutic drug monitoring?
Therapeutic drug monitoring (TDM) is testing that measures the amount of certain medicines in your blood. It is done to make sure the amount of medicine you are taking is both safe and effective.
How is therapeutic drug monitoring done?
The process component involves procedures such as assuring appropriate indications for ordering serum drug levels, timing of sample collections, communication of results to the clinician, and monitoring for appropriate clinician responses to treatment recommendations and for patient response to treatment.
How do you monitor the effects of medication?
Therapeutic drug monitoring are blood tests to measure the concentration of certain medications in your blood. You might need therapeutic drug monitoring if you are prescribed medication that is easily under or over dosed. Drugs that might cause significant side effects may also be monitored.
Why is therapeutic range important?
The use of therapeutic ranges has the widest potential application in the reliable and rapid establishment of optimal dosage schedules for individual patients. Serum concentrations above minimal therapeutic levels and below toxic levels are sought for all patients.
What is the minimum concentration of the drug for therapeutic effect?
Minimum effective concentration (MEC) is the minimum plasma concentration of a drug needed to achieve sufficient drug concentration at the receptors to produce the desired pharmacologic response, if drug molecules in plasma are in equilibrium with drug molecules in the various tissues (Figure 1.3).
What is used for therapeutic monitoring of drug?
Practice of therapeutic drug monitoring Nowadays, most other drugs can be readily measured in blood or plasma using versatile methods such as liquid chromatography–mass spectrometry or gas chromatography–mass spectrometry, which progressively replaced high-performance liquid chromatography.
What drugs require therapeutic monitoring?
Monitored Drugs by Category
|Immunosuppressants||Cyclosporine, tacrolimus, sirolimus, mycophenolate mofetil, azathioprine|
|Anti-cancer drugs||Methotrexate, all cytotoxic agents|
|Psychiatric drugs||Lithium, valproic acid, some antidepressants (imipramine, amitriptyline, nortriptyline, doxepin, desipramine)|
Why should we monitor the effects of medication?
All medications can cause side effects, which may lead to new symptoms or worsen existing symptoms, so it is important to monitor routinely all prescription drugs, over-the-counter medicines, and supplements. It is also important to be mindful of possible interactions.
What are the Specialised techniques of medication practice?
Level 3: Administering medication by specialised techniques.
- Rectal administration, e.g. suppositories, diazepam (for epileptic seizure)
- Insulin by injection.
- Administration through a Percutaneous Endoscopic Gastrostomy (PEG)
- Giving oxygen.
What is therapeutic benefit?
A therapeutic benefit is a benefit or effect obtained as a result of treatment. The term therapeutic defines any action or method used for the treatment of diseases or disorders. Thus, a therapeutic benefit is a positive result that occurs as a result of a method used to treat a disease or disorder.